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Discovery and Cardioprotective Effects of the First Non-Peptide Agonists of the G Protein-Coupled Prokineticin Receptor-1
Prokineticins are angiogenic hormones that activate two G protein-coupled receptors: PKR1 and PKR2. PKR1 has emerged as a critical mediator of cardiovascular homeostasis and cardioprotection. Identification of non-peptide PKR1 agonists that contribute to myocardial repair and collateral vessel growt...
Autores principales: | Gasser, Adeline, Brogi, Simone, Urayama, Kyoji, Nishi, Toshishide, Kurose, Hitoshi, Tafi, Andrea, Ribeiro, Nigel, Désaubry, Laurent, Nebigil, Canan G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382091/ https://www.ncbi.nlm.nih.gov/pubmed/25831128 http://dx.doi.org/10.1371/journal.pone.0121027 |
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