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Na(+)/H(+) Exchanger Isoform 1 Induced Cardiomyocyte Hypertrophy Involves Activation of p90 Ribosomal S6 Kinase

Studies using pharmacological and genetic approaches have shown that increased activity/expression of the Na(+)/H(+) exchanger isoform 1 (NHE1) play a critical role in the pathogenesis of cardiac hypertrophy. Despite the importance of NHE1 in cardiac hypertrophy, severe cerebrovascular side effects...

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Detalles Bibliográficos
Autores principales: Jaballah, Maiy, Mohamed, Iman A., Alemrayat, Bayan, Al-Sulaiti, Fatima, Mlih, Mohamed, Mraiche, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382094/
https://www.ncbi.nlm.nih.gov/pubmed/25830299
http://dx.doi.org/10.1371/journal.pone.0122230