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Na(+)/H(+) Exchanger Isoform 1 Induced Cardiomyocyte Hypertrophy Involves Activation of p90 Ribosomal S6 Kinase
Studies using pharmacological and genetic approaches have shown that increased activity/expression of the Na(+)/H(+) exchanger isoform 1 (NHE1) play a critical role in the pathogenesis of cardiac hypertrophy. Despite the importance of NHE1 in cardiac hypertrophy, severe cerebrovascular side effects...
Autores principales: | Jaballah, Maiy, Mohamed, Iman A., Alemrayat, Bayan, Al-Sulaiti, Fatima, Mlih, Mohamed, Mraiche, Fatima |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382094/ https://www.ncbi.nlm.nih.gov/pubmed/25830299 http://dx.doi.org/10.1371/journal.pone.0122230 |
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