Tobacco Smoke Activates Human Papillomavirus 16 p97 Promoter and Cooperates with High-Risk E6/E7 for Oxidative DNA Damage in Lung Cells

We have previously shown a functional interaction between human papillomavirus type 16 (HPV-16) E6 and E7 oncoproteins and cigarette smoke condensate (CSC) in lung cells suggesting cooperation during carcinogenesis. The molecular mechanisms of such interaction, however, remain to be elucidated. Here...

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Detalles Bibliográficos
Autores principales: Peña, Nelson, Carrillo, Diego, Muñoz, Juan P., Chnaiderman, Jonás, Urzúa, Ulises, León, Oscar, Tornesello, Maria L., Corvalán, Alejandro H., Soto-Rifo, Ricardo, Aguayo, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382149/
https://www.ncbi.nlm.nih.gov/pubmed/25830243
http://dx.doi.org/10.1371/journal.pone.0123029

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