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The SKINT1-Like Gene Is Inactivated in Hominoids But Not in All Primate Species: Implications for the Origin of Dendritic Epidermal T Cells

Dendritic epidermal T cells, which express an invariant Vγ5Vδ1 T-cell receptor and account for 95% of all resident T cells in the mouse epidermis, play a critical role in skin immune surveillance. These γδ T cells are generated by positive selection in the fetal thymus, after which they migrate to t...

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Detalles Bibliográficos
Autores principales: Mohamed, Rania Hassan, Sutoh, Yoichi, Itoh, Yasushi, Otsuka, Noriyuki, Miyatake, Yukiko, Ogasawara, Kazumasa, Kasahara, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382165/
https://www.ncbi.nlm.nih.gov/pubmed/25830554
http://dx.doi.org/10.1371/journal.pone.0123258

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