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High-Throughput In Vivo Genotoxicity Testing: An Automated Readout System for the Somatic Mutation and Recombination Test (SMART)

Genotoxicity testing is an important component of toxicity assessment. As illustrated by the European registration, evaluation, authorization, and restriction of chemicals (REACH) directive, it concerns all the chemicals used in industry. The commonly used in vivo mammalian tests appear to be ill ad...

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Detalles Bibliográficos
Autores principales: Lombardot, Benoit, Oh, Chun-Taek, Kwak, Jihoon, Genovesio, Auguste, Kang, Myungjoo, Hansen, Michael Adsett Edberg, Han, Sung-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382174/
https://www.ncbi.nlm.nih.gov/pubmed/25830368
http://dx.doi.org/10.1371/journal.pone.0121287