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CAPER Is Vital for Energy and Redox Homeostasis by Integrating Glucose-Induced Mitochondrial Functions via ERR-α-Gabpa and Stress-Induced Adaptive Responses via NF-κB-cMYC
Ever since we developed mitochondria to generate ATP, eukaryotes required intimate mito-nuclear communication. In addition, since reactive oxygen species are a cost of mitochondrial oxidative phosphorylation, this demands safeguards as protection from these harmful byproducts. Here we identified a c...
Autores principales: | Kang, Yun Kyoung, Putluri, Nagireddy, Maity, Suman, Tsimelzon, Anna, Ilkayeva, Olga, Mo, Qianxing, Lonard, David, Michailidis, George, Sreekumar, Arun, Newgard, Christopher B., Wang, Meng, Tsai, Sophia Y., Tsai, Ming-Jer, O'Malley, Bert W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382186/ https://www.ncbi.nlm.nih.gov/pubmed/25830341 http://dx.doi.org/10.1371/journal.pgen.1005116 |
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