Alpha1-chimaerin, a Rac1 GTPase-activating protein, is expressed at reduced mRNA levels in the brain of Alzheimer's disease patients

Alpha1-chimaerin is a GTPase-activating protein (GAP) for Rac1, a member of the Rho small GTPase family, whose action leads to the inactivation of Rac1. Rac1 activity is upregulated in Alzheimer's disease, but little is known about the role of α1-chimaerin. In this study, we investigated the ex...

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Detalles Bibliográficos
Autores principales: Kato, Tomoko, Konishi, Yoshihiro, Shimohama, Shun, Beach, Thomas G., Akatsu, Hiroyasu, Tooyama, Ikuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382517/
https://www.ncbi.nlm.nih.gov/pubmed/25676811
http://dx.doi.org/10.1016/j.neulet.2015.02.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382517/
https://www.ncbi.nlm.nih.gov/pubmed/25676811
http://dx.doi.org/10.1016/j.neulet.2015.02.013

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