The relationship of TP53 R72P polymorphism to disease outcome and TP53 mutation in myelodysplastic syndromes

Nonsynonymous TP53 exon 4 single-nucleotide polymorphism (SNP), R72P, is linked to cancer and mutagen susceptibility. R72P associations with specific cancer risk, particularly hematological malignancies, have been conflicting. Myelodysplastic syndrome (MDS) with chromosome 5q deletion is characteriz...

Descripción completa

Detalles Bibliográficos
Autores principales: McGraw, K L, Zhang, L M, Rollison, D E, Basiorka, A A, Fulp, W, Rawal, B, Jerez, A, Billingsley, D L, Lin, H-Y, Kurtin, S E, Yoder, S, Zhang, Y, Guinta, K, Mallo, M, Solé, F, Calasanz, M J, Cervera, J, Such, E, González, T, Nevill, T J, Haferlach, T, Smith, A E, Kulasekararaj, A, Mufti, G, Karsan, A, Maciejewski, J P, Sokol, L, Epling-Burnette, P K, Wei, S, List, A F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382654/
https://www.ncbi.nlm.nih.gov/pubmed/25768405
http://dx.doi.org/10.1038/bcj.2015.11

Ejemplares similares

Ejemplares similares