IL-23-mediated mononuclear phagocyte crosstalk protects mice from Citrobacter rodentium-induced colon immunopathology

Gut homeostasis and mucosal immune defense rely on the differential contributions of dendritic cells (DC) and macrophages. Here we show that colonic CX(3)CR1(+) mononuclear phagocytes are critical inducers of the innate response to Citrobacter rodentium infection. Specifically, the absence of IL-23...

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Detalles Bibliográficos
Autores principales: Aychek, Tegest, Mildner, Alexander, Yona, Simon, Kim, Ki-Wook, Lampl, Nardy, Reich-Zeliger, Shlomit, Boon, Louis, Yogev, Nir, Waisman, Ari, Cua, Daniel J., Jung, Steffen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382688/
https://www.ncbi.nlm.nih.gov/pubmed/25761673
http://dx.doi.org/10.1038/ncomms7525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382688/
https://www.ncbi.nlm.nih.gov/pubmed/25761673
http://dx.doi.org/10.1038/ncomms7525

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