Clinical use of Insulin Degludec: Practical Experience and Pragmatic Suggestions

Insulin degludec (IDeg) is an ultralong acting basal insulin. IDeg has unique pharmacokinetic and pharmacodynamic properties which allow once a daily dosage, at any time of the day. Its use is associated with a significantly lower risk of hypoglycemia. This review discusses the pragmatic use of IDeg...

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Detalles Bibliográficos
Autores principales: Kalra, Sanjay, Gupta, Yashdeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382770/
https://www.ncbi.nlm.nih.gov/pubmed/25838998
http://dx.doi.org/10.4103/1947-2714.153918
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author Kalra, Sanjay
Gupta, Yashdeep
author_facet Kalra, Sanjay
Gupta, Yashdeep
author_sort Kalra, Sanjay
collection PubMed
description Insulin degludec (IDeg) is an ultralong acting basal insulin. IDeg has unique pharmacokinetic and pharmacodynamic properties which allow once a daily dosage, at any time of the day. Its use is associated with a significantly lower risk of hypoglycemia. This review discusses the pragmatic use of IDeg, based on available evidence. A complete search of all nine original research papers (BEGIN® clinical trial program) pertaining to IDeg, listed in PubMed, was made to prepare this article.
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spelling pubmed-43827702015-04-02 Clinical use of Insulin Degludec: Practical Experience and Pragmatic Suggestions Kalra, Sanjay Gupta, Yashdeep N Am J Med Sci Review Article Insulin degludec (IDeg) is an ultralong acting basal insulin. IDeg has unique pharmacokinetic and pharmacodynamic properties which allow once a daily dosage, at any time of the day. Its use is associated with a significantly lower risk of hypoglycemia. This review discusses the pragmatic use of IDeg, based on available evidence. A complete search of all nine original research papers (BEGIN® clinical trial program) pertaining to IDeg, listed in PubMed, was made to prepare this article. Medknow Publications & Media Pvt Ltd 2015-03 /pmc/articles/PMC4382770/ /pubmed/25838998 http://dx.doi.org/10.4103/1947-2714.153918 Text en Copyright: © North American Journal of Medical Sciences http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Kalra, Sanjay
Gupta, Yashdeep
Clinical use of Insulin Degludec: Practical Experience and Pragmatic Suggestions
title Clinical use of Insulin Degludec: Practical Experience and Pragmatic Suggestions
title_full Clinical use of Insulin Degludec: Practical Experience and Pragmatic Suggestions
title_fullStr Clinical use of Insulin Degludec: Practical Experience and Pragmatic Suggestions
title_full_unstemmed Clinical use of Insulin Degludec: Practical Experience and Pragmatic Suggestions
title_short Clinical use of Insulin Degludec: Practical Experience and Pragmatic Suggestions
title_sort clinical use of insulin degludec: practical experience and pragmatic suggestions
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382770/
https://www.ncbi.nlm.nih.gov/pubmed/25838998
http://dx.doi.org/10.4103/1947-2714.153918
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