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MGAS: a powerful tool for multivariate gene-based genome-wide association analysis
Motivation: Standard genome-wide association studies, testing the association between one phenotype and a large number of single nucleotide polymorphisms (SNPs), are limited in two ways: (i) traits are often multivariate, and analysis of composite scores entails loss in statistical power and (ii) ge...
Autores principales: | Van der Sluis, Sophie, Dolan, Conor V., Li, Jiang, Song, Youqiang, Sham, Pak, Posthuma, Danielle, Li, Miao-Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382905/ https://www.ncbi.nlm.nih.gov/pubmed/25431328 http://dx.doi.org/10.1093/bioinformatics/btu783 |
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