High mobility group box 1 contributes to anti-neutrophil cytoplasmic antibody-induced neutrophils activation through receptor for advanced glycation end products (RAGE) and Toll-like receptor 4

INTRODUCTION: High mobility group box-1 (HMGB1), a typical damage-associated molecular pattern (DAMP) protein, is associated with inflammatory conditions and tissue damage. Our recent study found that circulating HMGB1 levels could reflect the disease activity of antineutrophil cytoplasmic antibody...

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Detalles Bibliográficos
Autores principales: Wang, Chen, Wang, Huan, Chang, Dong-Yuan, Hao, Jian, Zhao, Ming-Hui, Chen, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382936/
https://www.ncbi.nlm.nih.gov/pubmed/25889374
http://dx.doi.org/10.1186/s13075-015-0587-4

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