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Interaction of prion protein with acetylcholinesterase: potential pathobiological implications in prion diseases

INTRODUCTION: The prion protein (PrP) binds to various molecular partners, but little is known about their potential impact on the pathogenesis of prion diseases RESULTS: Here, we show that PrP can interact in vitro with acetylcholinesterase (AChE), a key protein of the cholinergic system in neural...

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Detalles Bibliográficos
Autores principales:	Torrent, Joan, Vilchez-Acosta, Alba, Muñoz-Torrero, Diego, Trovaslet, Marie, Nachon, Florian, Chatonnet, Arnaud, Grznarova, Katarina, Acquatella-Tran Van Ba, Isabelle, Le Goffic, Ronan, Herzog, Laetitia, Béringue, Vincent, Rezaei, Human
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383067/ https://www.ncbi.nlm.nih.gov/pubmed/25853328 http://dx.doi.org/10.1186/s40478-015-0188-0

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