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0.2% ropivacaine with fentanyl in the management of labor analgesia: A case study of 30 parturients

BACKGROUND: Epidural infusion of 0.2% ropivacaine is recommended by the manufacturers for labor analgesia. AIMS: The aim of this study is to evaluate the analgesic efficacy, degree of motor blockade, obstetric outcome in the form of incidence of normal vaginal, assisted vaginal and lower segment ces...

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Autores principales: Karhade, Seema Shreepad, Sardesai, Shalini Pravin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383103/
https://www.ncbi.nlm.nih.gov/pubmed/25886426
http://dx.doi.org/10.4103/0259-1162.151238
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author Karhade, Seema Shreepad
Sardesai, Shalini Pravin
author_facet Karhade, Seema Shreepad
Sardesai, Shalini Pravin
author_sort Karhade, Seema Shreepad
collection PubMed
description BACKGROUND: Epidural infusion of 0.2% ropivacaine is recommended by the manufacturers for labor analgesia. AIMS: The aim of this study is to evaluate the analgesic efficacy, degree of motor blockade, obstetric outcome in the form of incidence of normal vaginal, assisted vaginal and lower segment cesarean section. SETTINGS AND DESIGN: Pilot study. MATERIALS AND METHODS: In this pilot study, 30 nulliparous parturients in active labor had epidural analgesia established using 0.2% ropivacaine with 25 mcg fentanyl for initiation when cervical dilatation was 3–4 cm and then analgesia was maintained with 0.2% ropivacaine at 10 ml/h till the delivery of baby. STATISTICAL ANALYSIS: It was done by Wilcoxon sign rank test and paired t-test as applicable. RESULTS: There was a significant difference (P < 0.05) between prebolus, postbolus and postinfusion with respect to visual analog score. There was a significant difference (P > 0.05) between prebolus, postbolus, and postinfusion with respect to Bromage motor score, (Wilcoxon sign rank test). Six out of 30 paturients complained of tingling and heaviness in lower limbs after continuous infusion of 2–2.5 h. CONCLUSION: We conclude that 0.2% ropivacaine (8 ml) with fentanyl 25 mcg is good for initiation of ambulatory labor analgesia. But for maintenance of labor analgesia lower concentration of ropivacaine may be preferred.
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spelling pubmed-43831032015-04-13 0.2% ropivacaine with fentanyl in the management of labor analgesia: A case study of 30 parturients Karhade, Seema Shreepad Sardesai, Shalini Pravin Anesth Essays Res Original Article BACKGROUND: Epidural infusion of 0.2% ropivacaine is recommended by the manufacturers for labor analgesia. AIMS: The aim of this study is to evaluate the analgesic efficacy, degree of motor blockade, obstetric outcome in the form of incidence of normal vaginal, assisted vaginal and lower segment cesarean section. SETTINGS AND DESIGN: Pilot study. MATERIALS AND METHODS: In this pilot study, 30 nulliparous parturients in active labor had epidural analgesia established using 0.2% ropivacaine with 25 mcg fentanyl for initiation when cervical dilatation was 3–4 cm and then analgesia was maintained with 0.2% ropivacaine at 10 ml/h till the delivery of baby. STATISTICAL ANALYSIS: It was done by Wilcoxon sign rank test and paired t-test as applicable. RESULTS: There was a significant difference (P < 0.05) between prebolus, postbolus and postinfusion with respect to visual analog score. There was a significant difference (P > 0.05) between prebolus, postbolus, and postinfusion with respect to Bromage motor score, (Wilcoxon sign rank test). Six out of 30 paturients complained of tingling and heaviness in lower limbs after continuous infusion of 2–2.5 h. CONCLUSION: We conclude that 0.2% ropivacaine (8 ml) with fentanyl 25 mcg is good for initiation of ambulatory labor analgesia. But for maintenance of labor analgesia lower concentration of ropivacaine may be preferred. Medknow Publications & Media Pvt Ltd 2015 /pmc/articles/PMC4383103/ /pubmed/25886426 http://dx.doi.org/10.4103/0259-1162.151238 Text en Copyright: © Anesthesia: Essays and Researches http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Karhade, Seema Shreepad
Sardesai, Shalini Pravin
0.2% ropivacaine with fentanyl in the management of labor analgesia: A case study of 30 parturients
title 0.2% ropivacaine with fentanyl in the management of labor analgesia: A case study of 30 parturients
title_full 0.2% ropivacaine with fentanyl in the management of labor analgesia: A case study of 30 parturients
title_fullStr 0.2% ropivacaine with fentanyl in the management of labor analgesia: A case study of 30 parturients
title_full_unstemmed 0.2% ropivacaine with fentanyl in the management of labor analgesia: A case study of 30 parturients
title_short 0.2% ropivacaine with fentanyl in the management of labor analgesia: A case study of 30 parturients
title_sort 0.2% ropivacaine with fentanyl in the management of labor analgesia: a case study of 30 parturients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383103/
https://www.ncbi.nlm.nih.gov/pubmed/25886426
http://dx.doi.org/10.4103/0259-1162.151238
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