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Effect of Celastrol on Growth Inhibition of Prostate Cancer Cells through the Regulation of hERG Channel In Vitro

Objective. To explore the antiprostate cancer effects of Celastrol on prostate cancer cells' proliferation, apoptosis, and cell cycle distribution, as well as the correlation to the regulation of hERG. Methods. DU145 cells were treated with various concentrations of Celastrol (0.25–16.0 μmol/L)...

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Detalles Bibliográficos
Autores principales: Ji, Nan, Li, Jinjun, Wei, Zexiong, Kong, Fanhu, Jin, Hongyan, Chen, Xiaoya, Li, Yan, Deng, Youping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383143/
https://www.ncbi.nlm.nih.gov/pubmed/25866772
http://dx.doi.org/10.1155/2015/308475