Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor

The haptoglobin-haemoglobin receptor (HpHbR) of African trypanosomes allows acquisition of haem and provides an uptake route for trypanolytic factor-1, a mediator of innate immunity against trypanosome infection. In this study, we report the structure of Trypanosoma brucei HpHbR in complex with huma...

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Detalles Bibliográficos
Autores principales: Lane-Serff, Harriet, MacGregor, Paula, Lowe, Edward D, Carrington, Mark, Higgins, Matthew K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383175/
https://www.ncbi.nlm.nih.gov/pubmed/25497229
http://dx.doi.org/10.7554/eLife.05553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383175/
https://www.ncbi.nlm.nih.gov/pubmed/25497229
http://dx.doi.org/10.7554/eLife.05553

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