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Structural basis for ligand and innate immunity factor uptake by the trypanosome haptoglobin-haemoglobin receptor

The haptoglobin-haemoglobin receptor (HpHbR) of African trypanosomes allows acquisition of haem and provides an uptake route for trypanolytic factor-1, a mediator of innate immunity against trypanosome infection. In this study, we report the structure of Trypanosoma brucei HpHbR in complex with huma...

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Detalles Bibliográficos
Autores principales:	Lane-Serff, Harriet, MacGregor, Paula, Lowe, Edward D, Carrington, Mark, Higgins, Matthew K
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2014
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383175/ https://www.ncbi.nlm.nih.gov/pubmed/25497229 http://dx.doi.org/10.7554/eLife.05553

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