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Paracellular permeation-enhancing effect of AT1002 C-terminal amidation in nasal delivery

BACKGROUND: The identification of permeation enhancers has gained interest in the development of drug delivery systems. A six-mer peptide, H-FCIGRL-OH (AT1002), is a tight junction modulator with promising permeation-enhancing activity. AT1002 enhances the transport of molecular weight markers or ag...

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Detalles Bibliográficos
Autores principales:	Song, Keon-Hyoung, Kim, Sang-Bum, Shim, Chang-Koo, Chung, Suk-Jae, Kim, Dae-Duk, Rhee, Sang-Ki, Choi, Guang J, Kim, Chul-Hyun, Kim, Kiyoung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383222/ https://www.ncbi.nlm.nih.gov/pubmed/25848218 http://dx.doi.org/10.2147/DDDT.S79383

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