Cargando…

Childhood- versus Adolescent-Onset Antisocial Youth with Conduct Disorder: Psychiatric Illness, Neuropsychological and Psychosocial Function

OBJECTIVE: The present study investigates whether youths with childhood-onset antisocial behavior have higher rates of psychiatric illness, neuropsychological and psychosocial dysfunction than youths who engage in antisocial behavior for the first time in adolescence. Prior studies have generally fo...

Descripción completa

Detalles Bibliográficos
Autores principales: Johnson, Vicki A., Kemp, Andrew H., Heard, Robert, Lennings, Christopher J., Hickie, Ian B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383334/
https://www.ncbi.nlm.nih.gov/pubmed/25835393
http://dx.doi.org/10.1371/journal.pone.0121627
_version_ 1782364712399273984
author Johnson, Vicki A.
Kemp, Andrew H.
Heard, Robert
Lennings, Christopher J.
Hickie, Ian B.
author_facet Johnson, Vicki A.
Kemp, Andrew H.
Heard, Robert
Lennings, Christopher J.
Hickie, Ian B.
author_sort Johnson, Vicki A.
collection PubMed
description OBJECTIVE: The present study investigates whether youths with childhood-onset antisocial behavior have higher rates of psychiatric illness, neuropsychological and psychosocial dysfunction than youths who engage in antisocial behavior for the first time in adolescence. Prior studies have generally focused on single domains of function in heterogeneous samples. The present study also examined the extent to which adolescent-onset antisocial behavior can be considered normative, an assumption of Moffitt’s dual taxonomy model. METHOD: Forty-three subjects (34 males, 9 females, mean age = 15.31, age range 12–21) with a diagnosis of conduct disorder (CD) were recruited through Headspace Services and the Juvenile Justice Community Centre. We compared childhood-onset antisocial youths (n = 23) with adolescent-onset antisocial youths (n = 20) with a conduct disorder, across a battery of psychiatric, neuropsychological and psychosocial measures. Neuropsychological function of both groups was also compared with normative scores from control samples. RESULTS: The childhood-onset group displayed deficits in verbal learning and memory, higher rates of psychosis, childhood maltreatment and more serious violent behavior, all effects associated with a large effect size. Both groups had impaired executive function, falling within the extremely low range (severely impaired). CONCLUSIONS: Childhood-onset CD displayed greater cognitive impairment, more psychiatric symptoms and committed more serious violent offences. The finding of severe executive impairment in both childhood- and adolescent-onset groupings challenges the assumption that adolescent-onset antisocial behavior is a normative process.
format Online
Article
Text
id pubmed-4383334
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Public Library of Science
record_format MEDLINE/PubMed
spelling pubmed-43833342015-04-09 Childhood- versus Adolescent-Onset Antisocial Youth with Conduct Disorder: Psychiatric Illness, Neuropsychological and Psychosocial Function Johnson, Vicki A. Kemp, Andrew H. Heard, Robert Lennings, Christopher J. Hickie, Ian B. PLoS One Research Article OBJECTIVE: The present study investigates whether youths with childhood-onset antisocial behavior have higher rates of psychiatric illness, neuropsychological and psychosocial dysfunction than youths who engage in antisocial behavior for the first time in adolescence. Prior studies have generally focused on single domains of function in heterogeneous samples. The present study also examined the extent to which adolescent-onset antisocial behavior can be considered normative, an assumption of Moffitt’s dual taxonomy model. METHOD: Forty-three subjects (34 males, 9 females, mean age = 15.31, age range 12–21) with a diagnosis of conduct disorder (CD) were recruited through Headspace Services and the Juvenile Justice Community Centre. We compared childhood-onset antisocial youths (n = 23) with adolescent-onset antisocial youths (n = 20) with a conduct disorder, across a battery of psychiatric, neuropsychological and psychosocial measures. Neuropsychological function of both groups was also compared with normative scores from control samples. RESULTS: The childhood-onset group displayed deficits in verbal learning and memory, higher rates of psychosis, childhood maltreatment and more serious violent behavior, all effects associated with a large effect size. Both groups had impaired executive function, falling within the extremely low range (severely impaired). CONCLUSIONS: Childhood-onset CD displayed greater cognitive impairment, more psychiatric symptoms and committed more serious violent offences. The finding of severe executive impairment in both childhood- and adolescent-onset groupings challenges the assumption that adolescent-onset antisocial behavior is a normative process. Public Library of Science 2015-04-02 /pmc/articles/PMC4383334/ /pubmed/25835393 http://dx.doi.org/10.1371/journal.pone.0121627 Text en © 2015 Johnson et al http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.
spellingShingle Research Article
Johnson, Vicki A.
Kemp, Andrew H.
Heard, Robert
Lennings, Christopher J.
Hickie, Ian B.
Childhood- versus Adolescent-Onset Antisocial Youth with Conduct Disorder: Psychiatric Illness, Neuropsychological and Psychosocial Function
title Childhood- versus Adolescent-Onset Antisocial Youth with Conduct Disorder: Psychiatric Illness, Neuropsychological and Psychosocial Function
title_full Childhood- versus Adolescent-Onset Antisocial Youth with Conduct Disorder: Psychiatric Illness, Neuropsychological and Psychosocial Function
title_fullStr Childhood- versus Adolescent-Onset Antisocial Youth with Conduct Disorder: Psychiatric Illness, Neuropsychological and Psychosocial Function
title_full_unstemmed Childhood- versus Adolescent-Onset Antisocial Youth with Conduct Disorder: Psychiatric Illness, Neuropsychological and Psychosocial Function
title_short Childhood- versus Adolescent-Onset Antisocial Youth with Conduct Disorder: Psychiatric Illness, Neuropsychological and Psychosocial Function
title_sort childhood- versus adolescent-onset antisocial youth with conduct disorder: psychiatric illness, neuropsychological and psychosocial function
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383334/
https://www.ncbi.nlm.nih.gov/pubmed/25835393
http://dx.doi.org/10.1371/journal.pone.0121627
work_keys_str_mv AT johnsonvickia childhoodversusadolescentonsetantisocialyouthwithconductdisorderpsychiatricillnessneuropsychologicalandpsychosocialfunction
AT kempandrewh childhoodversusadolescentonsetantisocialyouthwithconductdisorderpsychiatricillnessneuropsychologicalandpsychosocialfunction
AT heardrobert childhoodversusadolescentonsetantisocialyouthwithconductdisorderpsychiatricillnessneuropsychologicalandpsychosocialfunction
AT lenningschristopherj childhoodversusadolescentonsetantisocialyouthwithconductdisorderpsychiatricillnessneuropsychologicalandpsychosocialfunction
AT hickieianb childhoodversusadolescentonsetantisocialyouthwithconductdisorderpsychiatricillnessneuropsychologicalandpsychosocialfunction