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Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis
A total of 244 patients with lupus nephritis (219 women (89.8%) with a female to male ratio of 9 : 1) were included in the study. Clinical and laboratory findings at renal biopsy are clinically valuable in identifying different renal classifications of lupus pathology, activity, and chronicity index...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383344/ https://www.ncbi.nlm.nih.gov/pubmed/25874130 http://dx.doi.org/10.1155/2015/857316 |
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author | Satirapoj, Bancha Tasanavipas, Pamila Supasyndh, Ouppatham |
author_facet | Satirapoj, Bancha Tasanavipas, Pamila Supasyndh, Ouppatham |
author_sort | Satirapoj, Bancha |
collection | PubMed |
description | A total of 244 patients with lupus nephritis (219 women (89.8%) with a female to male ratio of 9 : 1) were included in the study. Clinical and laboratory findings at renal biopsy are clinically valuable in identifying different renal classifications of lupus pathology, activity, and chronicity index. Patients with class IVG had significantly higher proportions of microscopic hematuria, proteinuria, hypertension, impaired renal function, anemia, hypoalbuminuria, and positive anti-DNA antibody. All of these findings correlated well with high activity index and chronicity index of lupus pathology. Considering these correlations may help to determine the clinicopathologic status of lupus patients. |
format | Online Article Text |
id | pubmed-4383344 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-43833442015-04-13 Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis Satirapoj, Bancha Tasanavipas, Pamila Supasyndh, Ouppatham Int J Nephrol Research Article A total of 244 patients with lupus nephritis (219 women (89.8%) with a female to male ratio of 9 : 1) were included in the study. Clinical and laboratory findings at renal biopsy are clinically valuable in identifying different renal classifications of lupus pathology, activity, and chronicity index. Patients with class IVG had significantly higher proportions of microscopic hematuria, proteinuria, hypertension, impaired renal function, anemia, hypoalbuminuria, and positive anti-DNA antibody. All of these findings correlated well with high activity index and chronicity index of lupus pathology. Considering these correlations may help to determine the clinicopathologic status of lupus patients. Hindawi Publishing Corporation 2015 2015-03-19 /pmc/articles/PMC4383344/ /pubmed/25874130 http://dx.doi.org/10.1155/2015/857316 Text en Copyright © 2015 Bancha Satirapoj et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Satirapoj, Bancha Tasanavipas, Pamila Supasyndh, Ouppatham Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis |
title | Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis |
title_full | Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis |
title_fullStr | Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis |
title_full_unstemmed | Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis |
title_short | Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis |
title_sort | clinicopathological correlation in asian patients with biopsy-proven lupus nephritis |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383344/ https://www.ncbi.nlm.nih.gov/pubmed/25874130 http://dx.doi.org/10.1155/2015/857316 |
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