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Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis

A total of 244 patients with lupus nephritis (219 women (89.8%) with a female to male ratio of 9 : 1) were included in the study. Clinical and laboratory findings at renal biopsy are clinically valuable in identifying different renal classifications of lupus pathology, activity, and chronicity index...

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Autores principales: Satirapoj, Bancha, Tasanavipas, Pamila, Supasyndh, Ouppatham
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383344/
https://www.ncbi.nlm.nih.gov/pubmed/25874130
http://dx.doi.org/10.1155/2015/857316
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author Satirapoj, Bancha
Tasanavipas, Pamila
Supasyndh, Ouppatham
author_facet Satirapoj, Bancha
Tasanavipas, Pamila
Supasyndh, Ouppatham
author_sort Satirapoj, Bancha
collection PubMed
description A total of 244 patients with lupus nephritis (219 women (89.8%) with a female to male ratio of 9 : 1) were included in the study. Clinical and laboratory findings at renal biopsy are clinically valuable in identifying different renal classifications of lupus pathology, activity, and chronicity index. Patients with class IVG had significantly higher proportions of microscopic hematuria, proteinuria, hypertension, impaired renal function, anemia, hypoalbuminuria, and positive anti-DNA antibody. All of these findings correlated well with high activity index and chronicity index of lupus pathology. Considering these correlations may help to determine the clinicopathologic status of lupus patients.
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spelling pubmed-43833442015-04-13 Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis Satirapoj, Bancha Tasanavipas, Pamila Supasyndh, Ouppatham Int J Nephrol Research Article A total of 244 patients with lupus nephritis (219 women (89.8%) with a female to male ratio of 9 : 1) were included in the study. Clinical and laboratory findings at renal biopsy are clinically valuable in identifying different renal classifications of lupus pathology, activity, and chronicity index. Patients with class IVG had significantly higher proportions of microscopic hematuria, proteinuria, hypertension, impaired renal function, anemia, hypoalbuminuria, and positive anti-DNA antibody. All of these findings correlated well with high activity index and chronicity index of lupus pathology. Considering these correlations may help to determine the clinicopathologic status of lupus patients. Hindawi Publishing Corporation 2015 2015-03-19 /pmc/articles/PMC4383344/ /pubmed/25874130 http://dx.doi.org/10.1155/2015/857316 Text en Copyright © 2015 Bancha Satirapoj et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Satirapoj, Bancha
Tasanavipas, Pamila
Supasyndh, Ouppatham
Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis
title Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis
title_full Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis
title_fullStr Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis
title_full_unstemmed Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis
title_short Clinicopathological Correlation in Asian Patients with Biopsy-Proven Lupus Nephritis
title_sort clinicopathological correlation in asian patients with biopsy-proven lupus nephritis
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383344/
https://www.ncbi.nlm.nih.gov/pubmed/25874130
http://dx.doi.org/10.1155/2015/857316
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