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Soluble α-Klotho Serum Levels in Chronic Kidney Disease
Transmembrane α-Klotho (TM-Klotho), expressed in renal tubules, is a cofactor for FGF23-receptor. Circulating soluble-α-Klotho (s-Klotho) results from TM-Klotho shedding and acts on Phosphate (P) and Calcium (Ca) tubular transport. Decreased TM-Klotho, described in experimental chronic kidney diseas...
Autores principales: | Rotondi, Silverio, Pasquali, Marzia, Tartaglione, Lida, Muci, Maria Luisa, Mandanici, Giusy, Leonangeli, Cristiana, Sales, Silvia, Farcomeni, Alessio, Mazzaferro, Sandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383388/ https://www.ncbi.nlm.nih.gov/pubmed/25873958 http://dx.doi.org/10.1155/2015/872193 |
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