Construction of a CXCL12-KDEL Fusion Gene to Inhibit Head and Neck Squamous Cell Carcinoma Metastasis by Intracellular Sequestration of CXCR4

The CXCL12-CXCR4 biological axis consisting of the chemotactic factor CXCL12 and its specific receptor CXCR4 plays an important role in oral cancer metastasis. High expression of CXCR4 may help oral squamous cancer cells invade local tissues and metastasize to lymph nodes. No obvious association was...

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Detalles Bibliográficos
Autores principales: Zhang, Wenchao, Wang, Xudong, Yue, Kai, Liu, Su, Liu, Xiaonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383411/
https://www.ncbi.nlm.nih.gov/pubmed/25866764
http://dx.doi.org/10.1155/2015/195828

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