Regulation of Protein Quality Control by UBE4B and LSD1 through p53-Mediated Transcription

Protein quality control is essential for clearing misfolded and aggregated proteins from the cell, and its failure is associated with many neurodegenerative disorders. Here, we identify two genes, ufd-2 and spr-5, that when inactivated, synergistically and robustly suppress neurotoxicity associated...

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Detalles Bibliográficos
Autores principales: Periz, Goran, Lu, Jiayin, Zhang, Tao, Kankel, Mark W., Jablonski, Angela M., Kalb, Robert, McCampbell, Alexander, Wang, Jiou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383508/
https://www.ncbi.nlm.nih.gov/pubmed/25837623
http://dx.doi.org/10.1371/journal.pbio.1002114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383508/
https://www.ncbi.nlm.nih.gov/pubmed/25837623
http://dx.doi.org/10.1371/journal.pbio.1002114

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