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XAV939-Mediated ARTD Activity Inhibition in Human MB Cell Lines

Diphtheria toxin-like ADP-ribosyltransferases 1 and 5 (ARTD-1, ARTD-5) are poly ADP-ribose enzymes (PARP) involved in non-homologous end-joining (NHEJ), which is the major pathway of double-strand break (DSB) repair. In addition, ARTD-5, or Tankyrase (TNKS), is a positive regulator of the WNT signal...

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Detalles Bibliográficos
Autores principales:	Renna, Cristiano, Salaroli, Roberta, Cocchi, Claudia, Cenacchi, Giovanna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383513/ https://www.ncbi.nlm.nih.gov/pubmed/25835728 http://dx.doi.org/10.1371/journal.pone.0124149

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