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Thyroid Hormone and P-Glycoprotein in Tumor Cells

P-glycoprotein (P-gp; multidrug resistance pump 1, MDR1; ABCB1) is a plasma membrane efflux pump that when activated in cancer cells exports chemotherapeutic agents. Transcription of the P-gp gene (MDR1) and activity of the P-gp protein are known to be affected by thyroid hormone. A cell surface rec...

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Detalles Bibliográficos
Autores principales:	Davis, Paul J., Incerpi, Sandra, Lin, Hung-Yun, Tang, Heng-Yuan, Sudha, Thangirala, Mousa, Shaker A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2015
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383522/ https://www.ncbi.nlm.nih.gov/pubmed/25866761 http://dx.doi.org/10.1155/2015/168427

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