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Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis

Dysregulation of the complement system is evident in many CNS diseases but mechanisms regulating complement activation in the CNS remain unclear. In a recent large rat genome-wide expression profiling and linkage analysis we found co-regulation of complement C3 immediately downstream of butyrylcholi...

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Detalles Bibliográficos
Autores principales: Aeinehband, Shahin, Lindblom, Rickard P. F., Al Nimer, Faiez, Vijayaraghavan, Swetha, Sandholm, Kerstin, Khademi, Mohsen, Olsson, Tomas, Nilsson, Bo, Ekdahl, Kristina Nilsson, Darreh-Shori, Taher, Piehl, Fredrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383591/
https://www.ncbi.nlm.nih.gov/pubmed/25835709
http://dx.doi.org/10.1371/journal.pone.0122048

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