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Complement Component C3 and Butyrylcholinesterase Activity Are Associated with Neurodegeneration and Clinical Disability in Multiple Sclerosis
Dysregulation of the complement system is evident in many CNS diseases but mechanisms regulating complement activation in the CNS remain unclear. In a recent large rat genome-wide expression profiling and linkage analysis we found co-regulation of complement C3 immediately downstream of butyrylcholi...
Autores principales: | Aeinehband, Shahin, Lindblom, Rickard P. F., Al Nimer, Faiez, Vijayaraghavan, Swetha, Sandholm, Kerstin, Khademi, Mohsen, Olsson, Tomas, Nilsson, Bo, Ekdahl, Kristina Nilsson, Darreh-Shori, Taher, Piehl, Fredrik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383591/ https://www.ncbi.nlm.nih.gov/pubmed/25835709 http://dx.doi.org/10.1371/journal.pone.0122048 |
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