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Spontaneous Cdc42 Polarization Independent of GDI-Mediated Extraction and Actin-Based Trafficking

The small Rho-family GTPase Cdc42 is critical for cell polarization and polarizes spontaneously in absence of upstream spatial cues. Spontaneous polarization is thought to require dynamic Cdc42 recycling through Guanine nucleotide Dissociation Inhibitor (GDI)-mediated membrane extraction and vesicle...

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Detalles Bibliográficos
Autores principales:	Bendezú, Felipe O., Vincenzetti, Vincent, Vavylonis, Dimitrios, Wyss, Romain, Vogel, Horst, Martin, Sophie G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383620/ https://www.ncbi.nlm.nih.gov/pubmed/25837586 http://dx.doi.org/10.1371/journal.pbio.1002097

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