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T-cell STAT3 is required for the maintenance of humoral immunity to LCMV
STAT3 is a critical transcription factor activated downstream of cytokine signaling and is integral for the function of multiple immune cell types. Human mutations in STAT3 cause primary immunodeficiency resulting in impaired control of a variety of infections, including reactivation of latent virus...
Autores principales: | McIlwain, David R, Grusdat, Melanie, Pozdeev, Vitaly I, Xu, Haifeng C, Shinde, Prashant, Reardon, Colin, Hao, Zhenyue, Beyer, Marc, Bergthaler, Andreas, Häussinger, Dieter, Nolan, Garry P, Lang, Karl S, Lang, Philipp A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383653/ https://www.ncbi.nlm.nih.gov/pubmed/25393615 http://dx.doi.org/10.1002/eji.201445060 |
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