Cargando…

A generalised enzyme kinetic model for predicting the behaviour of complex biochemical systems

Quasi steady-state enzyme kinetic models are increasingly used in systems modelling. The Michaelis Menten model is popular due to its reduced parameter dimensionality, but its low-enzyme and irreversibility assumption may not always be valid in the in vivo context. Whilst the total quasi-steady stat...

Descripción completa

Detalles Bibliográficos
Autores principales: Wong, Martin Kin Lok, Krycer, James Robert, Burchfield, James Geoffrey, James, David Ernest, Kuncic, Zdenka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383669/
https://www.ncbi.nlm.nih.gov/pubmed/25859426
http://dx.doi.org/10.1016/j.fob.2015.03.002