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A generalised enzyme kinetic model for predicting the behaviour of complex biochemical systems
Quasi steady-state enzyme kinetic models are increasingly used in systems modelling. The Michaelis Menten model is popular due to its reduced parameter dimensionality, but its low-enzyme and irreversibility assumption may not always be valid in the in vivo context. Whilst the total quasi-steady stat...
Autores principales: | Wong, Martin Kin Lok, Krycer, James Robert, Burchfield, James Geoffrey, James, David Ernest, Kuncic, Zdenka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383669/ https://www.ncbi.nlm.nih.gov/pubmed/25859426 http://dx.doi.org/10.1016/j.fob.2015.03.002 |
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