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Who will benefit from antidepressants in the acute treatment of bipolar depression? A reanalysis of the STEP-BD study by Sachs et al. 2007, using Q-learning

BACKGROUND: There is substantial uncertainty regarding the efficacy of antidepressants in the treatment of bipolar disorders. METHODS: Traditional randomized controlled trials and statistical methods are not designed to discover if, when, and to whom an intervention should be applied; thus, other me...

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Detalles Bibliográficos
Autores principales: Wu, Fan, Laber, Eric B, Lipkovich, Ilya A, Severus, Emanuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383759/
https://www.ncbi.nlm.nih.gov/pubmed/25844303
http://dx.doi.org/10.1186/s40345-014-0018-5