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Who will benefit from antidepressants in the acute treatment of bipolar depression? A reanalysis of the STEP-BD study by Sachs et al. 2007, using Q-learning
BACKGROUND: There is substantial uncertainty regarding the efficacy of antidepressants in the treatment of bipolar disorders. METHODS: Traditional randomized controlled trials and statistical methods are not designed to discover if, when, and to whom an intervention should be applied; thus, other me...
Autores principales: | Wu, Fan, Laber, Eric B, Lipkovich, Ilya A, Severus, Emanuel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383759/ https://www.ncbi.nlm.nih.gov/pubmed/25844303 http://dx.doi.org/10.1186/s40345-014-0018-5 |
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