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MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae

MyMpn (http://mympn.crg.eu) is an online resource devoted to studying the human pathogen Mycoplasma pneumoniae, a minimal bacterium causing lower respiratory tract infections. Due to its small size, its ability to grow in vitro, and the amount of data produced over the past decades, M. pneumoniae is...

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Autores principales: Wodke, Judith A. H., Alibés, Andreu, Cozzuto, Luca, Hermoso, Antonio, Yus, Eva, Lluch-Senar, Maria, Serrano, Luis, Roma, Guglielmo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383923/
https://www.ncbi.nlm.nih.gov/pubmed/25378328
http://dx.doi.org/10.1093/nar/gku1105
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author Wodke, Judith A. H.
Alibés, Andreu
Cozzuto, Luca
Hermoso, Antonio
Yus, Eva
Lluch-Senar, Maria
Serrano, Luis
Roma, Guglielmo
author_facet Wodke, Judith A. H.
Alibés, Andreu
Cozzuto, Luca
Hermoso, Antonio
Yus, Eva
Lluch-Senar, Maria
Serrano, Luis
Roma, Guglielmo
author_sort Wodke, Judith A. H.
collection PubMed
description MyMpn (http://mympn.crg.eu) is an online resource devoted to studying the human pathogen Mycoplasma pneumoniae, a minimal bacterium causing lower respiratory tract infections. Due to its small size, its ability to grow in vitro, and the amount of data produced over the past decades, M. pneumoniae is an interesting model organisms for the development of systems biology approaches for unicellular organisms. Our database hosts a wealth of omics-scale datasets generated by hundreds of experimental and computational analyses. These include data obtained from gene expression profiling experiments, gene essentiality studies, protein abundance profiling, protein complex analysis, metabolic reactions and network modeling, cell growth experiments, comparative genomics and 3D tomography. In addition, the intuitive web interface provides access to several visualization and analysis tools as well as to different data search options. The availability and—even more relevant—the accessibility of properly structured and organized data are of up-most importance when aiming to understand the biology of an organism on a global scale. Therefore, MyMpn constitutes a unique and valuable new resource for the large systems biology and microbiology community.
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spelling pubmed-43839232015-04-08 MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae Wodke, Judith A. H. Alibés, Andreu Cozzuto, Luca Hermoso, Antonio Yus, Eva Lluch-Senar, Maria Serrano, Luis Roma, Guglielmo Nucleic Acids Res Database Issue MyMpn (http://mympn.crg.eu) is an online resource devoted to studying the human pathogen Mycoplasma pneumoniae, a minimal bacterium causing lower respiratory tract infections. Due to its small size, its ability to grow in vitro, and the amount of data produced over the past decades, M. pneumoniae is an interesting model organisms for the development of systems biology approaches for unicellular organisms. Our database hosts a wealth of omics-scale datasets generated by hundreds of experimental and computational analyses. These include data obtained from gene expression profiling experiments, gene essentiality studies, protein abundance profiling, protein complex analysis, metabolic reactions and network modeling, cell growth experiments, comparative genomics and 3D tomography. In addition, the intuitive web interface provides access to several visualization and analysis tools as well as to different data search options. The availability and—even more relevant—the accessibility of properly structured and organized data are of up-most importance when aiming to understand the biology of an organism on a global scale. Therefore, MyMpn constitutes a unique and valuable new resource for the large systems biology and microbiology community. Oxford University Press 2014-11-06 2015-01-28 /pmc/articles/PMC4383923/ /pubmed/25378328 http://dx.doi.org/10.1093/nar/gku1105 Text en © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Database Issue
Wodke, Judith A. H.
Alibés, Andreu
Cozzuto, Luca
Hermoso, Antonio
Yus, Eva
Lluch-Senar, Maria
Serrano, Luis
Roma, Guglielmo
MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae
title MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae
title_full MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae
title_fullStr MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae
title_full_unstemmed MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae
title_short MyMpn: a database for the systems biology model organism Mycoplasma pneumoniae
title_sort mympn: a database for the systems biology model organism mycoplasma pneumoniae
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383923/
https://www.ncbi.nlm.nih.gov/pubmed/25378328
http://dx.doi.org/10.1093/nar/gku1105
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