The RCSB Protein Data Bank: views of structural biology for basic and applied research and education

The RCSB Protein Data Bank (RCSB PDB, http://www.rcsb.org) provides access to 3D structures of biological macromolecules and is one of the leading resources in biology and biomedicine worldwide. Our efforts over the past 2 years focused on enabling a deeper understanding of structural biology and pr...

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Autores principales: Rose, Peter W., Prlić, Andreas, Bi, Chunxiao, Bluhm, Wolfgang F., Christie, Cole H., Dutta, Shuchismita, Green, Rachel Kramer, Goodsell, David S., Westbrook, John D., Woo, Jesse, Young, Jasmine, Zardecki, Christine, Berman, Helen M., Bourne, Philip E., Burley, Stephen K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Database Issue
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383988/
https://www.ncbi.nlm.nih.gov/pubmed/25428375
http://dx.doi.org/10.1093/nar/gku1214
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author Rose, Peter W.
Prlić, Andreas
Bi, Chunxiao
Bluhm, Wolfgang F.
Christie, Cole H.
Dutta, Shuchismita
Green, Rachel Kramer
Goodsell, David S.
Westbrook, John D.
Woo, Jesse
Young, Jasmine
Zardecki, Christine
Berman, Helen M.
Bourne, Philip E.
Burley, Stephen K.
author_facet Rose, Peter W.
Prlić, Andreas
Bi, Chunxiao
Bluhm, Wolfgang F.
Christie, Cole H.
Dutta, Shuchismita
Green, Rachel Kramer
Goodsell, David S.
Westbrook, John D.
Woo, Jesse
Young, Jasmine
Zardecki, Christine
Berman, Helen M.
Bourne, Philip E.
Burley, Stephen K.
author_sort Rose, Peter W.
collection PubMed
description The RCSB Protein Data Bank (RCSB PDB, http://www.rcsb.org) provides access to 3D structures of biological macromolecules and is one of the leading resources in biology and biomedicine worldwide. Our efforts over the past 2 years focused on enabling a deeper understanding of structural biology and providing new structural views of biology that support both basic and applied research and education. Herein, we describe recently introduced data annotations including integration with external biological resources, such as gene and drug databases, new visualization tools and improved support for the mobile web. We also describe access to data files, web services and open access software components to enable software developers to more effectively mine the PDB archive and related annotations. Our efforts are aimed at expanding the role of 3D structure in understanding biology and medicine.
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spelling pubmed-43839882015-04-08 The RCSB Protein Data Bank: views of structural biology for basic and applied research and education Rose, Peter W. Prlić, Andreas Bi, Chunxiao Bluhm, Wolfgang F. Christie, Cole H. Dutta, Shuchismita Green, Rachel Kramer Goodsell, David S. Westbrook, John D. Woo, Jesse Young, Jasmine Zardecki, Christine Berman, Helen M. Bourne, Philip E. Burley, Stephen K. Nucleic Acids Res Database Issue The RCSB Protein Data Bank (RCSB PDB, http://www.rcsb.org) provides access to 3D structures of biological macromolecules and is one of the leading resources in biology and biomedicine worldwide. Our efforts over the past 2 years focused on enabling a deeper understanding of structural biology and providing new structural views of biology that support both basic and applied research and education. Herein, we describe recently introduced data annotations including integration with external biological resources, such as gene and drug databases, new visualization tools and improved support for the mobile web. We also describe access to data files, web services and open access software components to enable software developers to more effectively mine the PDB archive and related annotations. Our efforts are aimed at expanding the role of 3D structure in understanding biology and medicine. Oxford University Press 2014-11-26 2015-01-28 /pmc/articles/PMC4383988/ /pubmed/25428375 http://dx.doi.org/10.1093/nar/gku1214 Text en © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Database Issue
Rose, Peter W.
Prlić, Andreas
Bi, Chunxiao
Bluhm, Wolfgang F.
Christie, Cole H.
Dutta, Shuchismita
Green, Rachel Kramer
Goodsell, David S.
Westbrook, John D.
Woo, Jesse
Young, Jasmine
Zardecki, Christine
Berman, Helen M.
Bourne, Philip E.
Burley, Stephen K.
The RCSB Protein Data Bank: views of structural biology for basic and applied research and education
title The RCSB Protein Data Bank: views of structural biology for basic and applied research and education
title_full The RCSB Protein Data Bank: views of structural biology for basic and applied research and education
title_fullStr The RCSB Protein Data Bank: views of structural biology for basic and applied research and education
title_full_unstemmed The RCSB Protein Data Bank: views of structural biology for basic and applied research and education
title_short The RCSB Protein Data Bank: views of structural biology for basic and applied research and education
title_sort rcsb protein data bank: views of structural biology for basic and applied research and education
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4383988/
https://www.ncbi.nlm.nih.gov/pubmed/25428375
http://dx.doi.org/10.1093/nar/gku1214
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