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CATH: comprehensive structural and functional annotations for genome sequences
The latest version of the CATH-Gene3D protein structure classification database (4.0, http://www.cathdb.info) provides annotations for over 235 000 protein domain structures and includes 25 million domain predictions. This article provides an update on the major developments in the 2 years since the...
| Autores principales: | , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384018/ https://www.ncbi.nlm.nih.gov/pubmed/25348408 http://dx.doi.org/10.1093/nar/gku947 |
| _version_ | 1782364834232270848 |
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| author | Sillitoe, Ian Lewis, Tony E. Cuff, Alison Das, Sayoni Ashford, Paul Dawson, Natalie L. Furnham, Nicholas Laskowski, Roman A. Lee, David Lees, Jonathan G. Lehtinen, Sonja Studer, Romain A. Thornton, Janet Orengo, Christine A. |
| author_facet | Sillitoe, Ian Lewis, Tony E. Cuff, Alison Das, Sayoni Ashford, Paul Dawson, Natalie L. Furnham, Nicholas Laskowski, Roman A. Lee, David Lees, Jonathan G. Lehtinen, Sonja Studer, Romain A. Thornton, Janet Orengo, Christine A. |
| author_sort | Sillitoe, Ian |
| collection | PubMed |
| description | The latest version of the CATH-Gene3D protein structure classification database (4.0, http://www.cathdb.info) provides annotations for over 235 000 protein domain structures and includes 25 million domain predictions. This article provides an update on the major developments in the 2 years since the last publication in this journal including: significant improvements to the predictive power of our functional families (FunFams); the release of our ‘current’ putative domain assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology benchmarking experiments (CATH-40) and a number of improvements to the web pages. |
| format | Online Article Text |
| id | pubmed-4384018 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | Oxford University Press |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-43840182015-04-08 CATH: comprehensive structural and functional annotations for genome sequences Sillitoe, Ian Lewis, Tony E. Cuff, Alison Das, Sayoni Ashford, Paul Dawson, Natalie L. Furnham, Nicholas Laskowski, Roman A. Lee, David Lees, Jonathan G. Lehtinen, Sonja Studer, Romain A. Thornton, Janet Orengo, Christine A. Nucleic Acids Res Database Issue The latest version of the CATH-Gene3D protein structure classification database (4.0, http://www.cathdb.info) provides annotations for over 235 000 protein domain structures and includes 25 million domain predictions. This article provides an update on the major developments in the 2 years since the last publication in this journal including: significant improvements to the predictive power of our functional families (FunFams); the release of our ‘current’ putative domain assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology benchmarking experiments (CATH-40) and a number of improvements to the web pages. Oxford University Press 2014-10-27 2015-01-28 /pmc/articles/PMC4384018/ /pubmed/25348408 http://dx.doi.org/10.1093/nar/gku947 Text en © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Database Issue Sillitoe, Ian Lewis, Tony E. Cuff, Alison Das, Sayoni Ashford, Paul Dawson, Natalie L. Furnham, Nicholas Laskowski, Roman A. Lee, David Lees, Jonathan G. Lehtinen, Sonja Studer, Romain A. Thornton, Janet Orengo, Christine A. CATH: comprehensive structural and functional annotations for genome sequences |
| title | CATH: comprehensive structural and functional annotations for genome sequences |
| title_full | CATH: comprehensive structural and functional annotations for genome sequences |
| title_fullStr | CATH: comprehensive structural and functional annotations for genome sequences |
| title_full_unstemmed | CATH: comprehensive structural and functional annotations for genome sequences |
| title_short | CATH: comprehensive structural and functional annotations for genome sequences |
| title_sort | cath: comprehensive structural and functional annotations for genome sequences |
| topic | Database Issue |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384018/ https://www.ncbi.nlm.nih.gov/pubmed/25348408 http://dx.doi.org/10.1093/nar/gku947 |
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