Cargando…
Platinum: a database of experimentally measured effects of mutations on structurally defined protein–ligand complexes
Drug resistance is a major challenge for the treatment of many diseases and a significant concern throughout the drug development process. The ability to understand and predict the effects of mutations on protein–ligand affinities and their roles in the emergence of resistance would significantly ai...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2014
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384026/ https://www.ncbi.nlm.nih.gov/pubmed/25324307 http://dx.doi.org/10.1093/nar/gku966 |