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lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs

Despite the prevalence of long noncoding RNA (lncRNA) genes in eukaryotic genomes, only a small proportion have been examined for biological function. lncRNAdb, available at http://lncrnadb.org, provides users with a comprehensive, manually curated reference database of 287 eukaryotic lncRNAs that h...

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Detalles Bibliográficos
Autores principales: Quek, Xiu Cheng, Thomson, Daniel W., Maag, Jesper L.V., Bartonicek, Nenad, Signal, Bethany, Clark, Michael B., Gloss, Brian S., Dinger, Marcel E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384040/
https://www.ncbi.nlm.nih.gov/pubmed/25332394
http://dx.doi.org/10.1093/nar/gku988
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author Quek, Xiu Cheng
Thomson, Daniel W.
Maag, Jesper L.V.
Bartonicek, Nenad
Signal, Bethany
Clark, Michael B.
Gloss, Brian S.
Dinger, Marcel E.
author_facet Quek, Xiu Cheng
Thomson, Daniel W.
Maag, Jesper L.V.
Bartonicek, Nenad
Signal, Bethany
Clark, Michael B.
Gloss, Brian S.
Dinger, Marcel E.
author_sort Quek, Xiu Cheng
collection PubMed
description Despite the prevalence of long noncoding RNA (lncRNA) genes in eukaryotic genomes, only a small proportion have been examined for biological function. lncRNAdb, available at http://lncrnadb.org, provides users with a comprehensive, manually curated reference database of 287 eukaryotic lncRNAs that have been described independently in the scientific literature. In addition to capturing a great proportion of the recent literature describing functions for individual lncRNAs, lncRNAdb now offers an improved user interface enabling greater accessibility to sequence information, expression data and the literature. The new features in lncRNAdb include the integration of Illumina Body Atlas expression profiles, nucleotide sequence information, a BLAST search tool and easy export of content via direct download or a REST API. lncRNAdb is now endorsed by RNAcentral and is in compliance with the International Nucleotide Sequence Database Collaboration.
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spelling pubmed-43840402015-04-08 lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs Quek, Xiu Cheng Thomson, Daniel W. Maag, Jesper L.V. Bartonicek, Nenad Signal, Bethany Clark, Michael B. Gloss, Brian S. Dinger, Marcel E. Nucleic Acids Res Database Issue Despite the prevalence of long noncoding RNA (lncRNA) genes in eukaryotic genomes, only a small proportion have been examined for biological function. lncRNAdb, available at http://lncrnadb.org, provides users with a comprehensive, manually curated reference database of 287 eukaryotic lncRNAs that have been described independently in the scientific literature. In addition to capturing a great proportion of the recent literature describing functions for individual lncRNAs, lncRNAdb now offers an improved user interface enabling greater accessibility to sequence information, expression data and the literature. The new features in lncRNAdb include the integration of Illumina Body Atlas expression profiles, nucleotide sequence information, a BLAST search tool and easy export of content via direct download or a REST API. lncRNAdb is now endorsed by RNAcentral and is in compliance with the International Nucleotide Sequence Database Collaboration. Oxford University Press 2014-10-20 2015-01-28 /pmc/articles/PMC4384040/ /pubmed/25332394 http://dx.doi.org/10.1093/nar/gku988 Text en © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Database Issue
Quek, Xiu Cheng
Thomson, Daniel W.
Maag, Jesper L.V.
Bartonicek, Nenad
Signal, Bethany
Clark, Michael B.
Gloss, Brian S.
Dinger, Marcel E.
lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs
title lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs
title_full lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs
title_fullStr lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs
title_full_unstemmed lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs
title_short lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs
title_sort lncrnadb v2.0: expanding the reference database for functional long noncoding rnas
topic Database Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384040/
https://www.ncbi.nlm.nih.gov/pubmed/25332394
http://dx.doi.org/10.1093/nar/gku988
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