Cargando…
lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs
Despite the prevalence of long noncoding RNA (lncRNA) genes in eukaryotic genomes, only a small proportion have been examined for biological function. lncRNAdb, available at http://lncrnadb.org, provides users with a comprehensive, manually curated reference database of 287 eukaryotic lncRNAs that h...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384040/ https://www.ncbi.nlm.nih.gov/pubmed/25332394 http://dx.doi.org/10.1093/nar/gku988 |
_version_ | 1782364839043137536 |
---|---|
author | Quek, Xiu Cheng Thomson, Daniel W. Maag, Jesper L.V. Bartonicek, Nenad Signal, Bethany Clark, Michael B. Gloss, Brian S. Dinger, Marcel E. |
author_facet | Quek, Xiu Cheng Thomson, Daniel W. Maag, Jesper L.V. Bartonicek, Nenad Signal, Bethany Clark, Michael B. Gloss, Brian S. Dinger, Marcel E. |
author_sort | Quek, Xiu Cheng |
collection | PubMed |
description | Despite the prevalence of long noncoding RNA (lncRNA) genes in eukaryotic genomes, only a small proportion have been examined for biological function. lncRNAdb, available at http://lncrnadb.org, provides users with a comprehensive, manually curated reference database of 287 eukaryotic lncRNAs that have been described independently in the scientific literature. In addition to capturing a great proportion of the recent literature describing functions for individual lncRNAs, lncRNAdb now offers an improved user interface enabling greater accessibility to sequence information, expression data and the literature. The new features in lncRNAdb include the integration of Illumina Body Atlas expression profiles, nucleotide sequence information, a BLAST search tool and easy export of content via direct download or a REST API. lncRNAdb is now endorsed by RNAcentral and is in compliance with the International Nucleotide Sequence Database Collaboration. |
format | Online Article Text |
id | pubmed-4384040 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-43840402015-04-08 lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs Quek, Xiu Cheng Thomson, Daniel W. Maag, Jesper L.V. Bartonicek, Nenad Signal, Bethany Clark, Michael B. Gloss, Brian S. Dinger, Marcel E. Nucleic Acids Res Database Issue Despite the prevalence of long noncoding RNA (lncRNA) genes in eukaryotic genomes, only a small proportion have been examined for biological function. lncRNAdb, available at http://lncrnadb.org, provides users with a comprehensive, manually curated reference database of 287 eukaryotic lncRNAs that have been described independently in the scientific literature. In addition to capturing a great proportion of the recent literature describing functions for individual lncRNAs, lncRNAdb now offers an improved user interface enabling greater accessibility to sequence information, expression data and the literature. The new features in lncRNAdb include the integration of Illumina Body Atlas expression profiles, nucleotide sequence information, a BLAST search tool and easy export of content via direct download or a REST API. lncRNAdb is now endorsed by RNAcentral and is in compliance with the International Nucleotide Sequence Database Collaboration. Oxford University Press 2014-10-20 2015-01-28 /pmc/articles/PMC4384040/ /pubmed/25332394 http://dx.doi.org/10.1093/nar/gku988 Text en © The Author(s) 2014. Published by Oxford University Press on behalf of Nucleic Acids Research. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com |
spellingShingle | Database Issue Quek, Xiu Cheng Thomson, Daniel W. Maag, Jesper L.V. Bartonicek, Nenad Signal, Bethany Clark, Michael B. Gloss, Brian S. Dinger, Marcel E. lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs |
title | lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs |
title_full | lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs |
title_fullStr | lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs |
title_full_unstemmed | lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs |
title_short | lncRNAdb v2.0: expanding the reference database for functional long noncoding RNAs |
title_sort | lncrnadb v2.0: expanding the reference database for functional long noncoding rnas |
topic | Database Issue |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384040/ https://www.ncbi.nlm.nih.gov/pubmed/25332394 http://dx.doi.org/10.1093/nar/gku988 |
work_keys_str_mv | AT quekxiucheng lncrnadbv20expandingthereferencedatabaseforfunctionallongnoncodingrnas AT thomsondanielw lncrnadbv20expandingthereferencedatabaseforfunctionallongnoncodingrnas AT maagjesperlv lncrnadbv20expandingthereferencedatabaseforfunctionallongnoncodingrnas AT bartoniceknenad lncrnadbv20expandingthereferencedatabaseforfunctionallongnoncodingrnas AT signalbethany lncrnadbv20expandingthereferencedatabaseforfunctionallongnoncodingrnas AT clarkmichaelb lncrnadbv20expandingthereferencedatabaseforfunctionallongnoncodingrnas AT glossbrians lncrnadbv20expandingthereferencedatabaseforfunctionallongnoncodingrnas AT dingermarcele lncrnadbv20expandingthereferencedatabaseforfunctionallongnoncodingrnas |