Human BK Polyomavirus Plasmid pBKV (34-2) (Dunlop) Contains Mutations Not Found in the Originally Published Sequences

The plasmid pBKV (34-2) (ATCC 45025) contains the entire BK polyomavirus Dunlop genome. Sequencing revealed 12 point mutations compared to the GenBank sequence, but only 4 point mutations compared to the published sequence. The origin of these differences is unknown, but may impact virological as we...

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Detalles Bibliográficos
Autores principales: Henriksen, Stian, Mittelholzer, Christian, Gosert, Rainer, Hirsch, Hans H., Rinaldo, Christine Hanssen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2015
Materias:
Viruses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384130/
https://www.ncbi.nlm.nih.gov/pubmed/25814590
http://dx.doi.org/10.1128/genomeA.00046-15
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author Henriksen, Stian
Mittelholzer, Christian
Gosert, Rainer
Hirsch, Hans H.
Rinaldo, Christine Hanssen
author_facet Henriksen, Stian
Mittelholzer, Christian
Gosert, Rainer
Hirsch, Hans H.
Rinaldo, Christine Hanssen
author_sort Henriksen, Stian
collection PubMed
description The plasmid pBKV (34-2) (ATCC 45025) contains the entire BK polyomavirus Dunlop genome. Sequencing revealed 12 point mutations compared to the GenBank sequence, but only 4 point mutations compared to the published sequence. The origin of these differences is unknown, but may impact virological as well as diagnostic research and development.
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spelling pubmed-43841302015-04-03 Human BK Polyomavirus Plasmid pBKV (34-2) (Dunlop) Contains Mutations Not Found in the Originally Published Sequences Henriksen, Stian Mittelholzer, Christian Gosert, Rainer Hirsch, Hans H. Rinaldo, Christine Hanssen Genome Announc Viruses The plasmid pBKV (34-2) (ATCC 45025) contains the entire BK polyomavirus Dunlop genome. Sequencing revealed 12 point mutations compared to the GenBank sequence, but only 4 point mutations compared to the published sequence. The origin of these differences is unknown, but may impact virological as well as diagnostic research and development. American Society for Microbiology 2015-03-26 /pmc/articles/PMC4384130/ /pubmed/25814590 http://dx.doi.org/10.1128/genomeA.00046-15 Text en Copyright © 2015 Henriksen et al. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution 3.0 Unported license (http://creativecommons.org/licenses/by/3.0/) .
spellingShingle Viruses
Henriksen, Stian
Mittelholzer, Christian
Gosert, Rainer
Hirsch, Hans H.
Rinaldo, Christine Hanssen
Human BK Polyomavirus Plasmid pBKV (34-2) (Dunlop) Contains Mutations Not Found in the Originally Published Sequences
title Human BK Polyomavirus Plasmid pBKV (34-2) (Dunlop) Contains Mutations Not Found in the Originally Published Sequences
title_full Human BK Polyomavirus Plasmid pBKV (34-2) (Dunlop) Contains Mutations Not Found in the Originally Published Sequences
title_fullStr Human BK Polyomavirus Plasmid pBKV (34-2) (Dunlop) Contains Mutations Not Found in the Originally Published Sequences
title_full_unstemmed Human BK Polyomavirus Plasmid pBKV (34-2) (Dunlop) Contains Mutations Not Found in the Originally Published Sequences
title_short Human BK Polyomavirus Plasmid pBKV (34-2) (Dunlop) Contains Mutations Not Found in the Originally Published Sequences
title_sort human bk polyomavirus plasmid pbkv (34-2) (dunlop) contains mutations not found in the originally published sequences
topic Viruses
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384130/
https://www.ncbi.nlm.nih.gov/pubmed/25814590
http://dx.doi.org/10.1128/genomeA.00046-15
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