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Evaluation of the effect of ambrisentan on digital microvascular flow in patients with systemic sclerosis using laser Doppler perfusion imaging: a 12-week randomized double-blind placebo controlled trial

INTRODUCTION: In patients with systemic sclerosis (SSc), digital ischemia results from an occlusive microvasculopathy that may not respond adequately to conventional vasodilators. Endothelin receptor antagonists can potentially modify the fibroproliferative vascular remodeling in SSc, and hence thei...

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Detalles Bibliográficos
Autores principales:	Bose, Nilanjana, Bena, James, Chatterjee, Soumya
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384235/ https://www.ncbi.nlm.nih.gov/pubmed/25876611 http://dx.doi.org/10.1186/s13075-015-0558-9

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