The role of autophagy induced by tumor microenvironment in different cells and stages of cancer

Development of a tumor is a very complex process, and invasion and metastasis of malignant tumors are hallmarks and are difficult problems to overcome. The tumor microenvironment plays an important role in controlling tumor fate and autophagy induced by the tumor microenvironment is attracting more...

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Autores principales: Yang, Xue, Yu, Dan-Dan, Yan, Fei, Jing, Ying-Ying, Han, Zhi-Peng, Sun, Kai, Liang, Lei, Hou, Jing, Wei, Li-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384293/
https://www.ncbi.nlm.nih.gov/pubmed/25844158
http://dx.doi.org/10.1186/s13578-015-0005-2
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author Yang, Xue
Yu, Dan-Dan
Yan, Fei
Jing, Ying-Ying
Han, Zhi-Peng
Sun, Kai
Liang, Lei
Hou, Jing
Wei, Li-Xin
author_facet Yang, Xue
Yu, Dan-Dan
Yan, Fei
Jing, Ying-Ying
Han, Zhi-Peng
Sun, Kai
Liang, Lei
Hou, Jing
Wei, Li-Xin
author_sort Yang, Xue
collection PubMed
description Development of a tumor is a very complex process, and invasion and metastasis of malignant tumors are hallmarks and are difficult problems to overcome. The tumor microenvironment plays an important role in controlling tumor fate and autophagy induced by the tumor microenvironment is attracting more and more attention. Autophagy can be induced by several stressors in the tumor microenvironment and autophagy modifies the tumor microenvironment, too. Autophagy has dual roles in tumor growth. In this review, we discussed the interaction between autophagy and the tumor microenvironment and the paradoxical roles of autophagy on tumor growth at different stages of tumor development.
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spelling pubmed-43842932015-04-04 The role of autophagy induced by tumor microenvironment in different cells and stages of cancer Yang, Xue Yu, Dan-Dan Yan, Fei Jing, Ying-Ying Han, Zhi-Peng Sun, Kai Liang, Lei Hou, Jing Wei, Li-Xin Cell Biosci Review Development of a tumor is a very complex process, and invasion and metastasis of malignant tumors are hallmarks and are difficult problems to overcome. The tumor microenvironment plays an important role in controlling tumor fate and autophagy induced by the tumor microenvironment is attracting more and more attention. Autophagy can be induced by several stressors in the tumor microenvironment and autophagy modifies the tumor microenvironment, too. Autophagy has dual roles in tumor growth. In this review, we discussed the interaction between autophagy and the tumor microenvironment and the paradoxical roles of autophagy on tumor growth at different stages of tumor development. BioMed Central 2015-03-28 /pmc/articles/PMC4384293/ /pubmed/25844158 http://dx.doi.org/10.1186/s13578-015-0005-2 Text en © Yang et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Yang, Xue
Yu, Dan-Dan
Yan, Fei
Jing, Ying-Ying
Han, Zhi-Peng
Sun, Kai
Liang, Lei
Hou, Jing
Wei, Li-Xin
The role of autophagy induced by tumor microenvironment in different cells and stages of cancer
title The role of autophagy induced by tumor microenvironment in different cells and stages of cancer
title_full The role of autophagy induced by tumor microenvironment in different cells and stages of cancer
title_fullStr The role of autophagy induced by tumor microenvironment in different cells and stages of cancer
title_full_unstemmed The role of autophagy induced by tumor microenvironment in different cells and stages of cancer
title_short The role of autophagy induced by tumor microenvironment in different cells and stages of cancer
title_sort role of autophagy induced by tumor microenvironment in different cells and stages of cancer
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384293/
https://www.ncbi.nlm.nih.gov/pubmed/25844158
http://dx.doi.org/10.1186/s13578-015-0005-2
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