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Ubiquitin-specific proteases as therapeutic targets for the treatment of breast cancer

Key mediators of signaling pathways in breast cancer involve post-translational protein modification, primarily mediated through phosphorylation and ubiquitination. While previous studies focused on phosphorylation events, more recent analysis suggests that ubiquitin plays a parallel and equally imp...

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Detalles Bibliográficos
Autores principales: Pal, Anupama, Donato, Nicholas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384352/
https://www.ncbi.nlm.nih.gov/pubmed/25606592
http://dx.doi.org/10.1186/s13058-014-0461-3