The importance of loop length on the stability of i-motif structures

Using UV and srCD spectroscopy it is found that loop length within the i-motif structure is important for both thermal and pH stability, but in contrast to previous statements, it is the shorter loops that exhibit the highest stability.

Detalles Bibliográficos
Autores principales: Gurung, Sarah P., Schwarz, Christine, Hall, James P., Cardin, Christine J., Brazier, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384421/
https://www.ncbi.nlm.nih.gov/pubmed/25686374
http://dx.doi.org/10.1039/c4cc07279k
Descripción
Sumario:Using UV and srCD spectroscopy it is found that loop length within the i-motif structure is important for both thermal and pH stability, but in contrast to previous statements, it is the shorter loops that exhibit the highest stability.

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