A map of directional genetic interactions in a metazoan cell

Gene–gene interactions shape complex phenotypes and modify the effects of mutations during development and disease. The effects of statistical gene–gene interactions on phenotypes have been used to assign genes to functional modules. However, directional, epistatic interactions, which reflect regula...

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Detalles Bibliográficos
Autores principales: Fischer, Bernd, Sandmann, Thomas, Horn, Thomas, Billmann, Maximilian, Chaudhary, Varun, Huber, Wolfgang, Boutros, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Genes and Chromosomes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384530/
https://www.ncbi.nlm.nih.gov/pubmed/25748138
http://dx.doi.org/10.7554/eLife.05464

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384530/
https://www.ncbi.nlm.nih.gov/pubmed/25748138
http://dx.doi.org/10.7554/eLife.05464

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