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Crystal structure of 2-benzylamino-4-p-tolyl-6,7-dihydro-5H-cyclopenta[b]pyridine-3-carbonitrile
The title compound, C(23)H(21)N(3), comprises a 2-amino-3-cyanopyridine ring fused with a cyclopentane ring. The later adopts an envelope conformation with the central methylene C atom as the flap. The benzyl and and p-tolyl rings are inclined to one another by 56.18 (15)°, and to the pyridine ri...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384633/ https://www.ncbi.nlm.nih.gov/pubmed/25878816 http://dx.doi.org/10.1107/S2056989015000572 |
Sumario: | The title compound, C(23)H(21)N(3), comprises a 2-amino-3-cyanopyridine ring fused with a cyclopentane ring. The later adopts an envelope conformation with the central methylene C atom as the flap. The benzyl and and p-tolyl rings are inclined to one another by 56.18 (15)°, and to the pyridine ring by 81.87 (14) and 47.60 (11)°, respectively. In the crystal, molecules are linked by pairs of N—H⋯N(nitrile) hydrogen bonds, forming inversion dimers with an R (2) (2)(12) ring motif. The dimers are linked by C—H⋯π and π–π interactions [centroid–centroid distance = 3.7211 (12) Å], forming a three-dimensional framework. |
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