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Release of human cytomegalovirus from latency by a KAP1/TRIM28 phosphorylation switch

Human cytomegalovirus (HCMV) is a highly prevalent pathogen that induces life-long infections notably through the establishment of latency in hematopoietic stem cells (HSC). Bouts of reactivation are normally controlled by the immune system, but can be fatal in immuno-compromised individuals such as...

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Detalles Bibliográficos
Autores principales: Rauwel, Benjamin, Jang, Suk Min, Cassano, Marco, Kapopoulou, Adamandia, Barde, Isabelle, Trono, Didier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384640/
https://www.ncbi.nlm.nih.gov/pubmed/25846574
http://dx.doi.org/10.7554/eLife.06068