YB-1 regulates stress granule formation and tumor progression by translationally activating G3BP1

Under cell stress, global protein synthesis is inhibited to preserve energy. One mechanism is to sequester and silence mRNAs in ribonucleoprotein complexes known as stress granules (SGs), which contain translationally silent mRNAs, preinitiation factors, and RNA-binding proteins. Y-box binding prote...

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Detalles Bibliográficos
Autores principales: Somasekharan, Syam Prakash, El-Naggar, Amal, Leprivier, Gabriel, Cheng, Hongwei, Hajee, Shamil, Grunewald, Thomas G.P., Zhang, Fan, Ng, Tony, Delattre, Olivier, Evdokimova, Valentina, Wang, Yuzhuo, Gleave, Martin, Sorensen, Poul H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384734/
https://www.ncbi.nlm.nih.gov/pubmed/25800057
http://dx.doi.org/10.1083/jcb.201411047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384734/
https://www.ncbi.nlm.nih.gov/pubmed/25800057
http://dx.doi.org/10.1083/jcb.201411047

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