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A little sugar goes a long way: The cell biology of O-GlcNAc

Unlike the complex glycans decorating the cell surface, the O-linked β-N-acetyl glucosamine (O-GlcNAc) modification is a simple intracellular Ser/Thr-linked monosaccharide that is important for disease-relevant signaling and enzyme regulation. O-GlcNAcylation requires uridine diphosphate–GlcNAc, a p...

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Detalles Bibliográficos
Autores principales: Bond, Michelle R., Hanover, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384737/
https://www.ncbi.nlm.nih.gov/pubmed/25825515
http://dx.doi.org/10.1083/jcb.201501101