Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome

BACKGROUND: Tubulointerstitial nephritis and uveitis [TINU] syndrome is a rare disorder that may also be underdiagnosed. Patients with TINU syndrome typically present with an acute bilateral nongranulomatous anterior uveitis following symptoms of systemic illness. FINDINGS: We report the case of a 1...

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Detalles Bibliográficos
Autores principales: Barut, Kenan, Rzayev, Turkay, Canpolat, Nur, Ozluk, Yasemin, Tugal-Tutkun, Ilknur, Kasapcopur, Ozgur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384971/
https://www.ncbi.nlm.nih.gov/pubmed/25861394
http://dx.doi.org/10.1186/s12348-015-0035-2
Descripción
Sumario:BACKGROUND: Tubulointerstitial nephritis and uveitis [TINU] syndrome is a rare disorder that may also be underdiagnosed. Patients with TINU syndrome typically present with an acute bilateral nongranulomatous anterior uveitis following symptoms of systemic illness. FINDINGS: We report the case of a 15-year-old girl who presented with acute granulomatous iridocyclitis and was diagnosed with TINU syndrome based on renal biopsy findings. Both her uveitis and interstitial nephritis promptly responded to high-dose corticosteroid treatment, and there were no relapses during follow-up of 20 months. CONCLUSIONS: TINU should be included in the differential diagnosis of patients who present with acute granulomatous uveitis.

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