Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome

BACKGROUND: Tubulointerstitial nephritis and uveitis [TINU] syndrome is a rare disorder that may also be underdiagnosed. Patients with TINU syndrome typically present with an acute bilateral nongranulomatous anterior uveitis following symptoms of systemic illness. FINDINGS: We report the case of a 1...

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Autores principales: Barut, Kenan, Rzayev, Turkay, Canpolat, Nur, Ozluk, Yasemin, Tugal-Tutkun, Ilknur, Kasapcopur, Ozgur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384971/
https://www.ncbi.nlm.nih.gov/pubmed/25861394
http://dx.doi.org/10.1186/s12348-015-0035-2
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author Barut, Kenan
Rzayev, Turkay
Canpolat, Nur
Ozluk, Yasemin
Tugal-Tutkun, Ilknur
Kasapcopur, Ozgur
author_facet Barut, Kenan
Rzayev, Turkay
Canpolat, Nur
Ozluk, Yasemin
Tugal-Tutkun, Ilknur
Kasapcopur, Ozgur
author_sort Barut, Kenan
collection PubMed
description BACKGROUND: Tubulointerstitial nephritis and uveitis [TINU] syndrome is a rare disorder that may also be underdiagnosed. Patients with TINU syndrome typically present with an acute bilateral nongranulomatous anterior uveitis following symptoms of systemic illness. FINDINGS: We report the case of a 15-year-old girl who presented with acute granulomatous iridocyclitis and was diagnosed with TINU syndrome based on renal biopsy findings. Both her uveitis and interstitial nephritis promptly responded to high-dose corticosteroid treatment, and there were no relapses during follow-up of 20 months. CONCLUSIONS: TINU should be included in the differential diagnosis of patients who present with acute granulomatous uveitis.
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spelling pubmed-43849712015-04-08 Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome Barut, Kenan Rzayev, Turkay Canpolat, Nur Ozluk, Yasemin Tugal-Tutkun, Ilknur Kasapcopur, Ozgur J Ophthalmic Inflamm Infect Brief Report BACKGROUND: Tubulointerstitial nephritis and uveitis [TINU] syndrome is a rare disorder that may also be underdiagnosed. Patients with TINU syndrome typically present with an acute bilateral nongranulomatous anterior uveitis following symptoms of systemic illness. FINDINGS: We report the case of a 15-year-old girl who presented with acute granulomatous iridocyclitis and was diagnosed with TINU syndrome based on renal biopsy findings. Both her uveitis and interstitial nephritis promptly responded to high-dose corticosteroid treatment, and there were no relapses during follow-up of 20 months. CONCLUSIONS: TINU should be included in the differential diagnosis of patients who present with acute granulomatous uveitis. Springer Berlin Heidelberg 2015-02-13 /pmc/articles/PMC4384971/ /pubmed/25861394 http://dx.doi.org/10.1186/s12348-015-0035-2 Text en © Barut et al.; licensee Springer. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Brief Report
Barut, Kenan
Rzayev, Turkay
Canpolat, Nur
Ozluk, Yasemin
Tugal-Tutkun, Ilknur
Kasapcopur, Ozgur
Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome
title Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome
title_full Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome
title_fullStr Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome
title_full_unstemmed Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome
title_short Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome
title_sort acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome
topic Brief Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4384971/
https://www.ncbi.nlm.nih.gov/pubmed/25861394
http://dx.doi.org/10.1186/s12348-015-0035-2
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